ZO-1, alpha+, Human Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-ZO-1, alpha+, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | ZO-1, alpha+, Human |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | reactivity: human. cross reactivity: dog, mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), Immunofluorescence (IF), P, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The polyclonal antibody recognizes human zona occludens 1 (ZO-1), an ~220 kDa tight junction protein belonging to the membrane-associated guanlyate kinase (MAGUK) family. Members of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain-containing proteins, like ZO-1, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [ZO-1, alpha+] |
| Catalog # | MBS584473 |
| Price | $555 |
| Order / More Info | ZO-1, alpha+, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Willott, E et al; Localization and differential expression of two isoforms of the tight junction protein ZO-1. Am J Physiol 1992, 262: C1119. 2. Balda, M et al; Two classes of tight junctions are revealed by ZO-1 isoforms. Am J Physiol 1993, 264: C918. 3. Pelletier, R et al; Differential distribution of the tight-junction-associated protein ZO-1 isoforms alpha- plus and alpha-plus in guinea pig Sertoli cells: a possible association with F-actin and G-actin. Biol Reprod 1997, 57: 367. 4. Van Itallie, C et al; Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells. J Cell Sci 1995, 108: 1735. 5. Kurihara, H et al; Diversity among tight junctions in rat kidney: glomerular slit diaphragms and endothelial junctions express only one isoform of the tight junction protein ZO-1. Proc Natl Acad USA 1992, 89: 7075. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies