AKT2 (pSer474) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | AKT2 (pSer474) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti AKT2 (pSer474) antibody recognizes AKT2 also known as RAC-beta serine/threonine-protein kinase and protein kinase B beta, when phosphorylated at serine 474. AKT2 is a serine/threonine protein kinase that plays a key role in the PI3K-Akt signaling pathway, known to regulate cell growth, proliferation and survival. AKT2 is specifically involved in the insulin receptor signaling pathway. AKT2 is phosphorylated at serine 474 by (MAPK)-activated protein kinase-2, integrin-linked kinase, p38 MAPK, PKCalpha, PKCbetaII, mTORC2, double-stranded DNA-dependent PK, autophosphorylation and ATM. Phosphorylation at threonine 309 and serine 474 are required for full activation of AKT2 (Suizu et al. 2009). |
| Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 474 of human AKT2 |
| Other Names | [AKT2 (pSer474)], [AKT2; AKT2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA; PKB beta] |
| Gene, Accession # | [AKT2], Gene ID: 208, NCBI: P31751.2, UniProt: P31751 |
| Catalog # | MBS225187 |
| Price | $375 |
| Order / More Info | AKT2 (pSer474) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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