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Antigenic Specificity | NFKBIB - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against NFKBIB. It was validated on Western Blot using a cell lysate as a positive control.Target Description: NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-bindin |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIB |
Other Names | [NF-kappa-B inhibitor beta isoform 1; NF-kappa-B inhibitor beta; NF-kappa-B inhibitor beta; NFKB inhibitor beta; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9] |
Gene, Accession # | [NFKBIB], Gene ID: 4793, NCBI: NP_002494, UniProt: Q15653 |
Catalog # | MBS3202025 |
Price | $335 |
Order / More Info | NFKBIB - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |