p90 RSK1 Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp90 RSK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, bovine
Isotypen/a
FormatATTO 594 conjugate
Size0.4 mL
Concentration250ug/mL
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
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DescriptionBackground Info: Detects a ~90kDa protein corresponding to the molecular mass of p90 RSK1 on SDS PAGE immunoblots. Scientific Background: The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1-4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to
Immunogenn/a
Other Names[RSK1 p90; HU1; MAPKAP; p90rsk; p90S6K; RSK1; RSK 1 p90], [RPS6KA1; RPS6KA1; RSK; HU-1; RSK1; MAPKAPK1A; MAPKAPK1A; RSK1; S6K-alpha-1; p90-RSK 1; p90RSK1; p90S6K; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; RSK-1]
Gene, Accession #Gene ID: 6195, NCBI: NP_002944.2, UniProt: Q15418
Catalog #MBS805421
Price$320
Order / More Infop90 RSK1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Roux, P. (2007). UCSD-Nature Molecule Pages. 2. Fro?din, M. and Gammeltoft, S. (1999) Mol. Cell. Endocrinol. 151: 65-77. 3. Merienne, K. et al. (1998) J. Med. Genet. 35: 890-894. 4. De Cesare, D. et al. (1998) Proc. Natl. Acad. Sci. 95: 12202-12207. 5. Joel, P. B. et al. (1998) Mol. Cell. Biol. 18: 1978-1984.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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