Edit |   |
Antigenic Specificity | p90 RSK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine |
Isotype | n/a |
Format | ATTO 594 conjugate |
Size | 0.4 mL |
Concentration | 250ug/mL |
Applications | Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects a ~90kDa protein corresponding to the molecular mass of p90 RSK1 on SDS PAGE immunoblots. Scientific Background: The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1-4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to |
Immunogen | n/a |
Other Names | [RSK1 p90; HU1; MAPKAP; p90rsk; p90S6K; RSK1; RSK 1 p90], [RPS6KA1; RPS6KA1; RSK; HU-1; RSK1; MAPKAPK1A; MAPKAPK1A; RSK1; S6K-alpha-1; p90-RSK 1; p90RSK1; p90S6K; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; RSK-1] |
Gene, Accession # | Gene ID: 6195, NCBI: NP_002944.2, UniProt: Q15418 |
Catalog # | MBS805421 |
Price | $320 |
Order / More Info | p90 RSK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Roux, P. (2007). UCSD-Nature Molecule Pages. 2. Fro?din, M. and Gammeltoft, S. (1999) Mol. Cell. Endocrinol. 151: 65-77. 3. Merienne, K. et al. (1998) J. Med. Genet. 35: 890-894. 4. De Cesare, D. et al. (1998) Proc. Natl. Acad. Sci. 95: 12202-12207. 5. Joel, P. B. et al. (1998) Mol. Cell. Biol. 18: 1978-1984. |