Edit |   |
---|---|
Antigenic Specificity | BCL2L11 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-neg |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCL2L11 |
Other Names | [bcl-2-like protein 11 isoform 11; Bcl-2-like protein 11; bcl-2-like protein 11; BCL2 like 11; Bcl2-interacting mediator of cell death] |
Gene, Accession # | [BCL2L11], Gene ID: 10018, NCBI: NP_001191035.1, UniProt: O43521 |
Catalog # | MBS3220840 |
Price | $335 |
Order / More Info | BCL2L11 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |