NADE Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NADE |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | ion exchange purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NADE Antibody: The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). Co-expression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization. It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed. Finally, although initially discovered as an mRNA expressed in |
| Immunogen | Immunogen: NADE antibody was raised against a peptide corresponding to 14 amino acids near the middle of human NADE. Buffer: NADE Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [NADE; Bex; BEX3; NADE; HGR74; DXS6984E; Protein BEX3; Brain-expressed X-linked protein 3; nerve growth factor receptor (TNFRSF16) associated protein 1], [NGFRAP1; NGFRAP1; Bex; BEX3; NADE; HGR74; DXS6984E; BEX3; DXS6984E; NADE] |
| Gene, Accession # | [NGFRAP1], Gene ID: 27018, NCBI: NP_996798, UniProt: Q00994 |
| Catalog # | MBS150522 |
| Price | $375 |
| Order / More Info | NADE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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