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Antigenic Specificity | CD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to CD4. Cluster of Differentiation 4 (CD4) is a glycoprotein composed of an amino-terminal extracellular domain (four domains: D1-D4 with Ig-like structures), a transmembrane part and a short cytoplasmic tail. CD4 is expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages and dendritic cells, and plays an important role in the development and activation of T cells. On T cells, CD4 is the co-receptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen-Major Histocompatibility Complex (MHC). Specifically, the D1 domain of CD4 interacts with the beta2-domain of the MHC class II molecule. CD4 ensures specificity of the TCR-antigen interaction, prolongs the conta |
Immunogen | Immunogen: A synthetic -peptide of human CD4 |
Other Names | [CD4; CD4; CD4; CD4; CD4mut;], [CD4; CD4; CD4mut] |
Gene, Accession # | Gene ID: 920, NCBI: NP_000607.1, UniProt: P01730 |
Catalog # | MBS125744 |
Price | $200, $275, $430 |
Order / More Info | CD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zamoyska, R. (1994) Immunity 1, 243-246. |