CD74 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD74 |
| Clone | [LN2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate) |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD74, also known as the MHC Class II-associated invariant chain (II), is a Type II transmembrane protein which binds to the peptide-binding groove of newly-synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen-presenting cells such as B-lymphocytes (from before the pre-B-cell stage to before the plasma-cell stage), macrophages and monocytes, together with many epithelial cells. CD74 stains predominantly germinal-center lymphocytes and B-cell lymphomas but rarely T-cell lymphomas. It stains the cell membrane but a paranuclear globular labeling is also noted. CD74 is useful in differentiating Atypical Fibroxanthoma from Malignant Fibrous H |
| Immunogen | n/a |
| Other Names | [CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), isoform CRA_c; HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen gamma chain; p33; HLA-DR-gamma; OTTHUMP00000224283; OTTHUMP00000224284; OTTHUMP00000224285; OTTHUMP00000224286; OTTHUMP00000224288; OTTHUMP00000224338; MHC HLA-DR gamma chain; Ia-associated invariant chain; gamma chain of class II antigens; HLA-DR antigens-associated invariant chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33], [CD74; CD74; II; DHLAG; HLADG; Ia-GAMMA; DHLAG] |
| Gene, Accession # | [CD74], Gene ID: 972, UniProt: P04233 |
| Catalog # | MBS370040 |
| Price | $130, $160, $180 |
| Order / More Info | CD74 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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