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Antigenic Specificity | MMP-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, chicken, dog |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~62 and 72 kDa of human MMP2 protein. This antibody reacts with human, rat, mouse. The other species are not tested. Matrix metalloproteinases (MMPs) belong to a family of proteinases that target many extracellular matrix proteins including additional proteinases, growth factors, cell surface receptors and adhesion molecules. MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. The MMP activity requires proteolytic cleavage of MMPs in order to generate activie MMPs by release of the inhibitory propeptide domain from the whole molecules. MMP-2, MMP-3, MMP-7, MMP-9 and MMP-13 have been characterized as important factors for normal ti |
Immunogen | Antigen Preparation: A synthetic peptide corresponding to C-term of human MMP2. This sequence is identical among human, rat, mouse, chicken, dog and bovine. |
Other Names | [Rabbit MMP-2; Matrix Metalloproteinase 2 (MMP2); Gelatinase A; 72 kDa type IV collagenase precursor], [Mmp2; Mmp2; MMP-2] |
Gene, Accession # | [MMP-2], Gene ID: 81686, UniProt: Q9JHC2 |
Catalog # | MBS462081 |
Price | $285 |
Order / More Info | MMP-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Brigitte Lelongt, et al. Matrix Metalloproteinases MMP2 and MMP9 Are Produced in Early Stages of Kidney Morphogenesis but Only MMP9 Is Required for Renal Organogenesis In Vitro. J. Cell Biol. 1997. 136 (6), 1363-1373. |