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Antigenic Specificity | HSP27 (Heat Shock Protein 27) |
Clone | [SPM252] |
Host Species | Mouse |
Reactive Species | human, chimpanzee, sheep, rat, mouse, chicken |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced -p29- and -24K- protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells. |
Immunogen | Immunogen: Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells. |
Other Names | [Heat shock 27kDa protein, Estrogen-regulated 24kDa protein, Heat shock 25kDa protein 1, Heat shock 28kDa protein 1, Heat shock protein beta-1, HMN2B, Hsp25, Hsp28, HspB1, Stress-responsive protein 27 (SRP27)], [HSPB1; HSPB1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSP27; HSP28; HspB1; HSP 27; SRP27] |
Gene, Accession # | [HSPB1], Gene ID: 3315, NCBI: NP_001531.1, UniProt: P04792 |
Catalog # | MBS438082 |
Price | $190, $340, $340 |
Order / More Info | HSP27 (Heat Shock Protein 27) Antibody from MYBIOSOURCE INC. |
Product Specific References | Edwards DP et. al. Biochem Biophys Research Commun, 93:804-812, 1980. Ciocca DR et. al. Breast Cancer Research and Treatment, 20:33-42, 1991 |