PDL-1 Antibody from MYBIOSOURCE INC.
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| Edit | |
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| Antigenic Specificity | PDL-1 |
| Clone | [ABM5F25] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Flow cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PD-L 1 (CD274/B7-H1 ) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immuneresponses through its receptor, PD-1 and PD-L 1 playa key role in the pathogenesis of inflammatory diseases (programmeddeath 1). It is widely expressed in the mononuclear phagocy1e system (MPS), may co-stimulate T cells and regulatesinflammatory responses. PD-L 1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion , facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases. |
| Immunogen | Immunogen: A partial length recombinant protein of PDL-1 (amino acid 13-224) was used as the immunogen for this antibody. Buffer: PBS containing 0.05% BSA and 0.05% sodium azide. |
| Other Names | [CD274,B7H1,PDCD1L1,PDCD1LG1,PDL1], [CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; B7H1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1] |
| Gene, Accession # | [CD274], Gene ID: 29126, NCBI: NP_001254635.1 |
| Catalog # | MBS668222 |
| Price | $290 |
| Order / More Info | PDL-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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