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Antigenic Specificity | EIF2AK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Immunogen | Immunogen: A synthetic peptide of human EIF2AK3 |
Other Names | [PEK; PERK; WRS] |
Gene, Accession # | [EIF2AK3], Gene ID: 9451, NCBI: Q9NZJ5.3, UniProt: Q9NZJ5 |
Catalog # | MBS9131877 |
Price | $200, $275, $430 |
Order / More Info | EIF2AK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |