PLK3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PLK3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PLK3 antibody detects endogenous levels of total PLK3. Function: Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates ATF2, BCL2L1, CDC25A, CDC25C, CHEK2, HIF1A, JUN, p53/TP53, p73/TP73, PTEN, TOP2A and VRK1. Involved in cell cycle regulation: required for entry into S phase and cytokinesis. Phosphorylates BCL2L1, leading to regulate the G2 checkpoint and progression to cytokinesis during mitosis. Plays a key role in response to stress: rapidly activated upon stress stimulation, such as ionizing radiation, reac |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Membrane. Tissue Specificity: Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. May have a short half-live. In cells of hematopoietic origin, strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Predicted Cross Reactivity: Pig, Zebrafish, Bov |
| Other Names | [CNK; Cytokine Inducible Kinase; Cytokine-inducible serine/threonine-protein kinase; FGF inducible kinase; FGF-inducible kinase; FNK; PLK-3; Plk3; PLK3_HUMAN; Polo Like Kinase 3; Polo-like kinase 3; PRK; Proliferation Related Kinase; Proliferation-related kinase; Serine/threonine-protein kinase PLK3] |
| Gene, Accession # | [PLK3], Gene ID: 1263, NCBI: NP_004064.2, UniProt: Q9H4B4 |
| Catalog # | MBS9605925 |
| Price | $240, $280 |
| Order / More Info | PLK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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