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Antigenic Specificity | CD38 |
Clone | [90] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ~42 kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation. |
Immunogen | n/a |
Other Names | [Rat CD38; CD38; CD38; CD38; CD-38; T10; CD 38; ADP-Ribosyl Cyclase; CD-38; CD 38] |
Gene, Accession # | [CD38], Gene ID: 952, NCBI: BAA18966.1 |
Catalog # | MBS5309242 |
Price | $245 |
Order / More Info | CD38 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |