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Antigenic Specificity | PAH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PAH antibody detects endogenous levels of total PAH. Description: PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.Function: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4a-hydroxytetrahydrobiopterin.Subunit Structure: Homodimer and homotetramer.Post-translational Modifications: Phosphorylation at Ser-16 increases basal activity and facilitates activation by the substrate phenylalanine.Similarity: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. |
Immunogen | Immunogen: A synthesized peptide derived from human PAH Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (88%), Horse (100%), Sheep (88%), Rabbit (100%), Dog (100%), Chicken (88%), Xenopus (88%) |
Other Names | [PAH; PH; PH4H_HUMAN; Phe 4 monooxygenase; Phe-4-monooxygenase; Phenylalanine 4 hydroxylase; Phenylalanine hydroxylase; Phenylalanine-4-hydroxylase; PKU; PKU1] |
Gene, Accession # | [PAH], Gene ID: 5053, NCBI: NP_000268.1, UniProt: P00439 |
Catalog # | MBS9607112 |
Price | $240, $280 |
Order / More Info | PAH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |