Eya4 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Eya4 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | dog, guinea pig, human, mouse, rabbit, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against Eya4. It was validated on Western BlotTarget Description: Eya4 is a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Eya4 promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. It may be involved in development of the eye. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Eya4 |
| Other Names | [eyes absent homolog 4 isoform 1; Eyes absent homolog 4; eyes absent homolog 4; EYA transcriptional coactivator and phosphatase 4] |
| Gene, Accession # | [EYA4], Gene ID: 14051, NCBI: NP_034297, UniProt: Q9Z191 |
| Catalog # | MBS3204950 |
| Price | $335 |
| Order / More Info | Eya4 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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