CD79alpha Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD79alpha |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD79a molecule, immunoglobulin-associated alpha, also known as mb-1, is expressed in B lymphocytes and is part of the B-cell antigen receptor complex.[1] This complex consists of a clonally restricted antigen-binding molecule (membrane Ig) associated noncovalently with an 'invariant' transducer/transporter complex. It is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. [2] It is interacts with and increases activity of some Src-family tyrosine kinases. And also represses BCR signaling during development of immature B-cells. [3] |
| Immunogen | Immunogen: A synthetic peptide (conjugated to KLH) corresponding to the region of CD79α. |
| Other Names | n/a |
| Gene, Accession # | [CD79 alpha] |
| Catalog # | MBS355200 |
| Price | $275 |
| Order / More Info | CD79alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Ha, H., Kubagawa, H., Burrows, P. D. Molecular cloning and expression pattern of a human gene homologous to the murine mb-1 gene. J. Immun. 148: 1526-1531, 1992. 2. Luisiri P., Lee Y.J., Eisfelder B.J., Clark M.R. Cooperativity and segregation of function within the Ig-alpha/beta heterodimer of the B cell antigen receptor complex. J. Biol. Chem. 271:5158-5163(1996) 3. Tseng J., Eisfelder B.J., Clark M.R. B-cell antigen receptor-induced apoptosis requires both Ig alpha and Ig beta. Blood 89:1513-1520(1997) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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