PAK2 (Ab-197) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PAK2 (Ab-197) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PAK2 (Ab-197) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total PAK2 protein. Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Phosphorylates JUN and plays an important role in EGF-induced ce |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human PAK2 around the phosphorylation site of serine 62 (T-R-S(p)-V-I). |
| Other Names | [EC 2.7.11.1; gamma-PAK; kinase PAK2; P21-activated kinase 2; p21-activated kinase 2] |
| Gene, Accession # | [PAK2], Gene ID: 5062, NCBI: NP_002568.2, UniProt: Q13177 |
| Catalog # | MBS9402130 |
| Price | $200, $255 |
| Order / More Info | PAK2 (Ab-197) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies