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Antigenic Specificity | DUX4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.26mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthetic peptide of human DUX4 |
Other Names | [Double homeobox 4; Double homeobox protein 10; Double homeobox protein 4; Double homeobox protein 4/10; DUX10; DUX4L; DUX4L1] |
Gene, Accession # | [DUX4], Gene ID: 100288687; 107987484; 107987485; 107987486; 107987487, NCBI: NP_149418.3, UniProt: Q9UBX2 |
Catalog # | MBS2559786 |
Price | $110, $150, $225 |
Order / More Info | DUX4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |