CD45RA (Leucocyte Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD45RA (Leucocyte Marker)
Clone[158-4D3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a protein of 205kDa-220kDa, identified as CD45RA [Workshop V; Code CD45.38]. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is usef
ImmunogenImmunogen: Stimulated human leukocytes
Other Names[B220, CD45R, GP180, Leukocyte common antigen (LCA), Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C (PTPRC), Receptor-type tyrosine-protein phosphatase C, T200 glycoprotein], [PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45; L-CA]
Gene, Accession #[PTPRC], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575
Catalog #MBS438154
Price$190, $340, $340
Order / More InfoCD45RA (Leucocyte Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesOxford University Press, Oxford, p511-515, 1995. Clement LT. J Clin Immunol. 1992, 12(1):1-10. Yamada A, et al. Cell Immunol. 1992, 142(1):114-24. Mahalingam M, et al. Clin Immunol Immunopathol. 1996,81(2):210-214. Jacob MC, et al. Am J Hematol. 1992, 39(1):45-5
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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