HSP60 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSP60
Clone[LK1]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, bovine, dog, chicken, Fruit Fly, guinea pig, hamster, monkey, porcine, rabbit, sheep, Xenopus, plant, silkworm
IsotypeIgG1
FormatAPC-Cy7 conjugate
Size0.2 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA (EIA), Flow Cytometry (FC/FACS)
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DescriptionDetects ~60 kDa. In both prokaryotic and eukaryotic cells, the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones. Members of the HSP60 family of heat shock proteins are some of the best characterized chaperones. HSP60, also known as Cpn60 or GroEl, is an abundant protein synthesized constitutively in the cell that is induced to a higher concentration after brief cell shock. It is present in many species and exhibits a remarkable sequence homology among various counterparts in bacteria, plants, and mammals with more than half of the residues identical between bacterial and mammalian HSP60 (1-3). Whereas mammalian HSP60 is localized within the mitochondria, p
ImmunogenImmunogen: Recombinant human HSP60
Other Names[Mouse Human HSP60 IgG1; HSP60 : APC/Cy7; CPN60; GROEL; HLD4; HSP 60; HSP65; HSPD1; HuCHA60; SPG 13]
Gene, Accession #[HSP60], Gene ID: 3329, NCBI: NP_002147.2, UniProt: P10809
Catalog #MBS8002152
Price$570
Order / More InfoHSP60 Antibody from MYBIOSOURCE INC.
Product Specific References1. Hartl, F.U. (1996) Nature 381: 571-579. 2. Bukau, B. and Horwich, A.L. (1998) Cell 92: 351-366. 3. Hartl, F.U. and Hayer-Hartl, M. (2002) Science 295: 1852-1858. 4. Jindal, S., et al. (1989) Molecular and Cellular Biology 9: 2279-2283. 5. La Verda, D., et al (1999) Infect Dis. Obstet. Gynecol. 7: 64-71. 6. Itoh, H. et al. (2002) Eur. J. Biochem. 269: 5931-5938. 7. Gupta, S. and Knowlton, A.A. J. Cell Mol Med. 9: 51-58. 8. Deocaris, C.C. et al. (2006) Cell Stress Chaperones 11: 116-128. 9. Lai, H.C. et al. (2007) Am. J. Physiol. Endocrinol. Metab. 292: E292-E297. 10. Gao, Y.L., et al (1995) J. of Immunology 154: 3548-3556. 11. Neuer, A., et al (1997) European Society for Human Reproduction and Embryology 12(5):925-929. 12. Bason, C., et al (2003) Lancet 362(9400): 1971-1977.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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