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Antigenic Specificity | Rat CD45 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | rat |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 50 tests, 100 tests, 200 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
Immunogen | n/a |
Other Names | [Rat CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; LCA; T200; Ly-5; Ptprc] |
Gene, Accession # | [CD45], Gene ID: 24699, NCBI: NP_001103357.1, UniProt: P04157 |
Catalog # | MBS2559601 |
Price | $75, $85, $100 |
Order / More Info | Rat CD45 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |