KLF7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKLF7
Clone[AT3G3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionKLK7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation, survival and the development of nervous systems.and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 is binds specifically to an Ikaros core binding element that is crucial for in vivo NTRK1/TrkA enhancer function. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
ImmunogenImmunogen: Recombinant human KLF7 (1-302aa) purified from E. coli
Other Names[Kruppel-like factor 7; uKLF], [KLF7; KLF7; UKLF; UKLF]
Gene, Accession #[KLF7], Gene ID: 8609, NCBI: NP_003700, UniProt: O75840
Catalog #MBS200270
Price$240, $315
Order / More InfoKLF7 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMatsumoto, N., et al. (1998) J Biol Chem 273 (43): 28229-37; Kanazawa, A., et al. (2005) Diabetologia 48 (7): 1315-22
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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