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Antigenic Specificity | CTNB1 (C-term), 646-673 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: Drosophila, bovine, mouse, rat, Xenopus) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CTNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-673 amino acids from the C-terminal region of human CTNB1. The protein encoded by this gene is part of a complex ofproteins that constitute adherens junctions (AJs). AJs arenecessary for the creation and maintenance of epithelial celllayers by regulating cell growth and adhesion between cells. Theencoded protein also anchors the actin cytoskeleton and may beresponsible for transmitting the contact inhibition signal thatcauses cells to stop dividing once the epithelial sheet iscomplete. Finally, this protein binds to the product of the APCgene, which is mutated in adenomatous polyposis of the colon.M |
Immunogen | n/a |
Other Names | [Catenin beta-1; Beta-catenin; CTNNB1; CTNNB] |
Gene, Accession # | [CTNNB1], Gene ID: 1499, NCBI: NP_001091679.1, UniProt: P35222 |
Catalog # | MBS9202403 |
Price | $165, $370 |
Order / More Info | CTNB1 (C-term), 646-673 Antibody from MYBIOSOURCE INC. |
Product Specific References | Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010) Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010) Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010) Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010) Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010) |