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Antigenic Specificity | SWAP70 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SWAP-70 is a 70 kDa multiple functional signaling proteins involved in formation of membrane ruffling induced by signal cascade of tyrosine kinase growth factor receptors. It is involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates. Though originally isolated from activated B lymphocytes, recently it has been found that it is widely expressed in various cell types and tissues. It has a high binding afinity to PI(3, 4)P2. Its intracellular localization has been reported to depend on cell activation. Stimulation of the B cell receptor triggers a translocation of SWAP-70 from the cytosol to the plasma membrane in B cells. This translocation required a func |
Immunogen | Immunogen Information: A partial length recombinant SWAP70 protein (amino acids 300-505) was used as the immunogen for this antibody. |
Other Names | [SWAP70; KIAA0640; HSPC321; Switch-associated protein 70], [SWAP70; SWAP70; HSPC321; SWAP-70; KIAA0640; SWAP-70] |
Gene, Accession # | [SWAP70], Gene ID: 23075, NCBI: Q9UH65.1, UniProt: Q9UH65 |
Catalog # | MBS668801 |
Price | $140, $270 |
Order / More Info | SWAP70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |