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Antigenic Specificity | Probable importin subunit beta-4, Plutella xylostella |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | Plutella Xylostella |
Isotype | IgG |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Importin is a type of karyopherin that transports protein molecules into the nucleus by binding to specific recognition sequences, called nuclear localization sequences (NLS). Importin has two subunits, importin alpha and importin beta. Members of the importin-beta family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo. The NLS-Importin alpha-Importin beta trimer dissociates after binding to Ran GTP inside the nucleus, with the two importin proteins being recycled to the cytoplasm for further use. |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to probable importin subunit beta-4 protein. |
Other Names | n/a |
Gene, Accession # | NCBI: SCV16910.1 |
Catalog # | MBS435437 |
Price | $440 |
Order / More Info | Probable importin subunit beta-4, Plutella xylostella Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |