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Antigenic Specificity | IGF2R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 3.2 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IGF2R protein. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human insulin-like growth factor 2 receptor |
Other Names | [MPR1; MPRI; CD222; CIMPR; M6P-R] |
Gene, Accession # | [IGF2R], Gene ID: 3482, NCBI: NP_000867.2, UniProt: P11717 |
Catalog # | MBS9403002 |
Price | $255 |
Order / More Info | IGF2R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |