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Antigenic Specificity | CXCR4 (N-term), 50-79 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, monkey, mouse, porcine, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CXCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4. This gene encodes a CXC chemokine receptor specific forstromal cell-derived factor-1. The protein has 7 transmembraneregions and is located on the cell surface. It acts with the CD4protein to support HIV entry into cells and is also highlyexpressed in breast cancer cells. Mutations in this gene have beenassociated with WHIM (warts, hypogammaglobulinemia, infections, andmyelokathexis) syndrome. Alternate transcriptional splice variants,encoding different isoforms, have been characterized. [provided byRefSeq]. |
Immunogen | n/a |
Other Names | [C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; Lipopolysaccharide-associated protein 3; LAP-3; LPS-associated protein 3; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD184; CXCR4] |
Gene, Accession # | [CXCR4], Gene ID: 7852, NCBI: NP_001008540.1, UniProt: P61073 |
Catalog # | MBS9203374 |
Price | $165, $370 |
Order / More Info | CXCR4 (N-term), 50-79 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hammad, M.M., et al. J. Biol. Chem. 285(45):34653-34664(2010) Wang, A., et al. Arthritis Rheum. 62(11):3436-3446(2010) Cheng, M., et al. Circ. Res. 107(9):1083-1093(2010) Sanematsu, F., et al. Circ. Res. 107(9):1102-1105(2010) O'Hayre, M., et al. PLoS ONE 5 (7), E11716 (2010) : |