NFX1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNFX1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against NFX1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: NFX1 binds to the X-box motif of MHC class II genes and represses their expression. NFX1 may play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. NFX1 mediates E2-dependent ubiquitination.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X an
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFX1
Other Names[Transcriptional repressor NF-X1; transcriptional repressor NF-X1; nuclear transcription factor, X-box binding 1; Nuclear transcription factor, X box-binding protein 1]
Gene, Accession #[NFX1], Gene ID: 4799, NCBI: NP_667344, UniProt: Q12986
Catalog #MBS3202279
Price$335
Order / More InfoNFX1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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