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Antigenic Specificity | IL-4/Interleukin 4 |
Clone | [IL4/1597] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNF, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2 a |
Immunogen | Immunogen: Recombinant full-length human IL-4 protein |
Other Names | [B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF1; Binetrakin; BSF1; IGG1 induction factor; Il4e12; Interleukin 4 variant 2; Interleukin 4; isoform 1Lymphocyte stimulatory factor 1; MGC79402; Pitrakinra] |
Gene, Accession # | [IL-4], Gene ID: 3565, NCBI: NP_000580.1, UniProt: P05112 |
Catalog # | MBS4381019 |
Price | $190, $340, $340 |
Order / More Info | IL-4/Interleukin 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | Yokota, T., et al. 1986. Proc. Natl. Acad. Sci. USA 83: 5894-5898. |