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Antigenic Specificity | Phospho-Cav1.2-pS1927 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 21-24 kDa integral proteins, caveolins, are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1,-2, and-3) have been identified with different tissue distributions. Caveolins form hetero-and homooligomers that interact with cholesterol and other lipids (1). Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease (2). Caveolins interact with multiple signaling molecules, such as Galpha subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS (1, 2). It is believed th |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding serine1927of mouse Cav1.2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [MBC; Cav1.2; Cchl1a1; MELC-CC] |
Gene, Accession # | [Cav1.2-pS1927], Gene ID: 12288, NCBI: NP_001153005.1, UniProt: Q01815 |
Catalog # | MBS8527457 |
Price | $310 |
Order / More Info | Phospho-Cav1.2-pS1927 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Okamoto, T. et al. (1998) J Biol Chem 273, 5419-22. 2. Smart, E.J. et al. (1999) Mol Cell Biol 19, 7289-304. 3. Nomura, R. et al. (1999) Mol. Biol. Cell 10, 975-986. 4. Volonte, D. et al. (2001) J. Biol. Chem. 276, 8094-8103. 5. Lee, H. et al. (2000) Mol Endocrinol 14, 1750-75. 6. Schlegel, A. et al. (2001) J Biol Chem 276, 4398-408. |