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Antigenic Specificity | P4HA3 (Center), 274-303 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.31 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This P4HA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the Central region of human P4HA3. This gene encodes a component of prolyl 4-hydroxylase, akey enzyme in collagen synthesis composed of two identical alphasubunits and two beta subunits. The encoded protein is one ofseveral different types of alpha subunits and provides the majorpart of the catalytic site of the active enzyme. In collagen andrelated proteins, prolyl 4-hydroxylase catalyzes the formation of4-hydroxyproline that is essential to the proper three-dimensionalfolding of newly synthesized procollagen chains. Alternativelyspliced transcript variants have been observed, but |
Immunogen | n/a |
Other Names | [Prolyl 4-hydroxylase subunit alpha-3; 4-PH alpha-3; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3; P4HA3] |
Gene, Accession # | [P4HA3], Gene ID: 283208, NCBI: NP_878907.1, UniProt: Q7Z4N8 |
Catalog # | MBS9212839 |
Price | $165, $370 |
Order / More Info | P4HA3 (Center), 274-303 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rose, J. Phd, et al. Mol. Med. (2010) In press : Koivunen, P., et al. J. Biol. Chem. 281(39):28712-28720(2006) Kukkola, L., et al. J. Biol. Chem. 278(48):47685-47693(2003) Van Den Diepstraten, C., et al. Circulation 108(5):508-511(2003) |