Integrin beta4 (Cytoplasmic Region) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Integrin beta4 (Cytoplasmic Region) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects a 200kDa* protein corresponding to the molecular mass of integrin-b4 on SDS-PAGE immunoblots of human A431 cells. Integrins are cell adhesion molecules that can mediate bidirectional transfer of signals across the plasma membrane. The cytoplasmic domains of integrin family members interact with components of the signal transduction apparatus within cells. Integrin alpha-6-beta-4receptors are found in basement membrane along with laminin-5. These receptors are expressed in epithelial, schwann, endothelial and some immune cells. The cytoplasmic domain of the integrin-beta4 subunit recruits the adaptor protein Shc and is required for assembly of hemidesmosomes. Tyrosine phosphorylation of multiple sites within the cytopla |
| Immunogen | Immunogen: Clone M126 was generated from a recombinant protein containing amino acid residues in the cytoplasmic region of human integrin-b4. Thissequence is found in all three integrin-b4 isoforms and has 90% homology with rat and mouse integrin-b4. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS470017 |
| Price | $325 |
| Order / More Info | Integrin beta4 (Cytoplasmic Region) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Dans, M. et al. (2001). J Biol Chem. 276(2):1494-1502.• Shaw, L.M. (2001). Mol Cell Biol. 21(15):5082-5093. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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