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Antigenic Specificity | DDB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of DDB2 protein. DDB2 encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding diffe |
Immunogen | Immunogen: Synthesized peptide derived from part region of human DDB2 protein at amino acid sequence of 260-340 |
Other Names | [Rabbit DDB2; DNA damage-binding protein 2; DDB p48 subunit; DDBb; Damage-specific DNA-binding protein 2; UV-damaged DNA-binding protein 2; UV-DDB 2] |
Gene, Accession # | [DDB2], Gene ID: 1643, NCBI: Q92466.1, UniProt: Q92466 |
Catalog # | MBS9708920 |
Price | $130, $220, $325 |
Order / More Info | DDB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |