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Antigenic Specificity | TMEM59 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding. |
Immunogen | Immunogen: TMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. Buffer: TMEM59 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TMEM59; C1orf8; HSPC001; C1orf8; UNQ169/PRO195; Transmembrane protein 59; Liver membrane-bound protein; transmembrane protein 59], [TMEM59; TMEM59; C1orf8; HSPC001; C1orf8] |
Gene, Accession # | [TMEM59], Gene ID: 9528, NCBI: NP_004863, UniProt: Q9BXS4 |
Catalog # | MBS150213 |
Price | $375 |
Order / More Info | TMEM59 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |