TMEM59 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTMEM59
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionTMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
ImmunogenImmunogen: TMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. Buffer: TMEM59 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[TMEM59; C1orf8; HSPC001; C1orf8; UNQ169/PRO195; Transmembrane protein 59; Liver membrane-bound protein; transmembrane protein 59], [TMEM59; TMEM59; C1orf8; HSPC001; C1orf8]
Gene, Accession #[TMEM59], Gene ID: 9528, NCBI: NP_004863, UniProt: Q9BXS4
Catalog #MBS150213
Price$375
Order / More InfoTMEM59 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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