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Antigenic Specificity | Uchl3 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Uchl3. It was validated on Western BlotTarget Description: Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Uchl3 has a 10-fold preference for Arg and Lys at position P3, and exhibits a preference towards 'Lys-48'-linked Ubiquitin chains. Uchl3 deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Uchl3 indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. It is requir |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Uchl3 |
Other Names | [ubiquitin carboxyl-terminal hydrolase isozyme L3; Ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); Ubiquitin thioesterase L3] |
Gene, Accession # | [UCHL3], Gene ID: 50933, NCBI: NP_057932, UniProt: Q9JKB1 |
Catalog # | MBS3214276 |
Price | $335 |
Order / More Info | Uchl3 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |