Uchl3 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUchl3 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against Uchl3. It was validated on Western BlotTarget Description: Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Uchl3 has a 10-fold preference for Arg and Lys at position P3, and exhibits a preference towards 'Lys-48'-linked Ubiquitin chains. Uchl3 deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Uchl3 indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. It is requir
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Uchl3
Other Names[ubiquitin carboxyl-terminal hydrolase isozyme L3; Ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); Ubiquitin thioesterase L3]
Gene, Accession #[UCHL3], Gene ID: 50933, NCBI: NP_057932, UniProt: Q9JKB1
Catalog #MBS3214276
Price$335
Order / More InfoUchl3 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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