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Antigenic Specificity | MYOZAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Multiple isoforms of MYOZAP are known to exist. MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A ups |
Immunogen | Immunogen: MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP. Buffer: MYOZAP Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MYOZAP; gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M; MYOZAP; Myocardial zonula adherens protein; GRINL1A upstream protein; Gup; GRINL1A complex locus], [GCOM1; MYZAP; gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M; MYOZAP; Gup] |
Gene, Accession # | [GCOM1], Gene ID: 145781, NCBI: NP_001018110, UniProt: P0CAP1 |
Catalog # | MBS151319 |
Price | $375 |
Order / More Info | MYOZAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |