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Antigenic Specificity | FRAT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FRAT1 antibody detects endogenous levels of total FRAT1. Function: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.Subunit Structure: Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.Post-translational Modifications: Phosphorylated.Similarity: Belongs to the GSK-3-binding protein family. |
Immunogen | Immunogen: A synthesized peptide derived from human FRAT1 Subcellular Location: Cytoplasmic Predicted Cross Reactivity: Pig, Bovine Similarity: Pig (100%), Bovine (92%) |
Other Names | [FRAT 1; frequently rearranged in advanced T cell lymphomas; Frequently rearranged in advanced T-cell lymphomas; GSK 3 binding protein FRAT1; proto oncogene FRAT1] |
Gene, Accession # | [FRAT1], Gene ID: 10023, NCBI: NP_005470.2, UniProt: Q92837 |
Catalog # | MBS9608545 |
Price | $240, $280 |
Order / More Info | FRAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |