FRAT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFRAT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: FRAT1 antibody detects endogenous levels of total FRAT1. Function: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.Subunit Structure: Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.Post-translational Modifications: Phosphorylated.Similarity: Belongs to the GSK-3-binding protein family.
ImmunogenImmunogen: A synthesized peptide derived from human FRAT1 Subcellular Location: Cytoplasmic Predicted Cross Reactivity: Pig, Bovine Similarity: Pig (100%), Bovine (92%)
Other Names[FRAT 1; frequently rearranged in advanced T cell lymphomas; Frequently rearranged in advanced T-cell lymphomas; GSK 3 binding protein FRAT1; proto oncogene FRAT1]
Gene, Accession #[FRAT1], Gene ID: 10023, NCBI: NP_005470.2, UniProt: Q92837
Catalog #MBS9608545
Price$240, $280
Order / More InfoFRAT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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