ADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motif 4) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motif 4) |
| Clone | [9H40] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Neutralization |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human ADAMTS4. Does not crossreact with recombinant human ADAMTS1, ADAMTS5, ADAMTS13 or ADAMTSL1.2. Species Sequence Homology: chimpanzee; 100%, canine; 97%, mouse, rat, bovine; 94%. ADAMTS4 is a secreted member of the ADAM family of proteins. ADAMTS4 is upregulated by TNF-alpha in osteoarthritis and contributes to joint destruction. Its upregulation in some cancers may enhance tumor invasiveness. Human ADAMTS4 consists of a signal peptide (aa1-51), a pro domain (aa52-212) and a mature chain (aa213-837) containing the following domains: catalytic (aa218-425), disintegrin (aa437-519), TSP type-1 (aa520-575), Cys-rich (aa577-685) and spacer (aa686-837). The amino acid sequence of rhADAMTS4 is 100%, 97% and 94% identical to that of |
| Immunogen | Immunogen: Recombinant corresponding to aa213-685 from human ADAMTS4 expressed in NSO cells (O75173). |
| Other Names | [-ADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motif 4)], [ADAMTS4; ADAMTS4; ADMP-1; ADAMTS-2; ADAMTS-4; KIAA0688; KIAA0688] |
| Gene, Accession # | Gene ID: 9507, NCBI: NP_005090.3, UniProt: O75173 |
| Catalog # | MBS608876 |
| Price | $810 |
| Order / More Info | ADAMTS4 (Aggrecanase I, A Disintegrin And Metalloproteinase with Thrombospondin motif 4) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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