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Antigenic Specificity | Human GAPDH (C-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | reacts with: mouse, porcine, rat. Based on sequence similarity, is expected to react with: dog. |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises an epitope within the C-terminal (CT) region of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Hunt |
Immunogen | Immunogen: Peptide sequence C-HQVVSSDFNSDT corresponding to the C-terminal region of GAPDH (NP 002037.2). Histology Positive Control Tissue: Human tonsil Buffer Solution: TRIS buffered saline Antiserum Preparation: Antisera to human GAPDH (CT) were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [GAPD], [GAPDH; GAPDH; G3PD; GAPD; HEL-S-162eP; GAPD; GAPDH] |
Gene, Accession # | [GAPDH], Gene ID: 2597, NCBI: NP_001243728.1, UniProt: P04406 |
Catalog # | MBS221355 |
Price | $550 |
Order / More Info | Human GAPDH (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |