Human GAPDH (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman GAPDH (C-TERMINAL)
Clonepolyclonal
Host SpeciesGoat
Reactive Speciesreacts with: mouse, porcine, rat. Based on sequence similarity, is expected to react with: dog.
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5mg/ml
ApplicationsELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)
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DescriptionThis item recognises an epitope within the C-terminal (CT) region of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Hunt
ImmunogenImmunogen: Peptide sequence C-HQVVSSDFNSDT corresponding to the C-terminal region of GAPDH (NP 002037.2). Histology Positive Control Tissue: Human tonsil Buffer Solution: TRIS buffered saline Antiserum Preparation: Antisera to human GAPDH (CT) were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human
Other Names[GAPD], [GAPDH; GAPDH; G3PD; GAPD; HEL-S-162eP; GAPD; GAPDH]
Gene, Accession #[GAPDH], Gene ID: 2597, NCBI: NP_001243728.1, UniProt: P04406
Catalog #MBS221355
Price$550
Order / More InfoHuman GAPDH (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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