Human Macrophage Inhibitory Cytokine-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Macrophage Inhibitory Cytokine-1 |
| Clone | [ME-6D10] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), CELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human Macrophage Inhibitory Cytokine-1 (MIC-1). Purified monoclonal mouse antibody.Background: Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-β superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance (1). MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines (1,2). MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the d |
| Immunogen | Immunogen: Immunogen: cDNA |
| Other Names | [GDF15], [GDF15; GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1] |
| Gene, Accession # | Gene ID: 9518, NCBI: NP_004855.2, UniProt: Q99988 |
| Catalog # | MBS468032 |
| Price | $505 |
| Order / More Info | Human Macrophage Inhibitory Cytokine-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hayes VM, Severi G, Southey MC, Padilla EJD, English DR, Hopper JL, Giles GG andSutherland RL (2006). Macrophage Inhibitory Cytokine-1 H6D Polymorphism, Prostate CancerRisk, and Survival. Cancer Epidemiology Biomarkers & Prevention 15, 1223-1225Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, He XY, Zhang HP,Donnellan M, Mahler S, Pryor K, Walsh BJ, Nicholson RC, Fairlie WD, Por SB, Robbins JMand Breit SN (1997). MIC-1, a novel macrophage inhibitory cytokine, is a divergent member ofthe TGF-beta superfamily. Proc Natl Acad Sci U S A 14;94(21):11514-9Bauskin AR, Brown DA, Kuffner T, Johnen H, Luo XW, Hunter M and Breit SN (2006). Roleof Macrophage Inhibitory Cytokine-1 in Tumorigenesis and Diagnosis of Cancer. CancerResearch 66, 4983-4986 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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