Human EphA2 receptor tyrosine kinase (EphA2) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman EphA2 receptor tyrosine kinase (EphA2)
Clone[K?-5H5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), CELISA, Immunofluorescence (IF)
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DescriptionSpecificity: anti-human EphA2. Background: EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDa transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it repre
ImmunogenImmunogen: Immunogen: cDNA
Other Names[Eph receptor tyrosine kinase A2], [EPHA2; EPHA2; ECK; CTPA; ARCC2; CTPP1; CTRCT6; ECK]
Gene, Accession #Gene ID: 1969, NCBI: NP_004422.2, UniProt: P29317
Catalog #MBS468027
Price$505
Order / More InfoHuman EphA2 receptor tyrosine kinase (EphA2) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLindberg RA and Hunter T (1990). cDNA cloning and characterization of eck, an epithelial cell receptorprotein- tyrosine kinase in the Eph/elk family of protein kinases. Mol Cell Biol 10:6316-24.Brantley-Sieders d, Schmidt s, Parker M and Chen J (2004). Eph receptor tyrosine kinases in tumor andtumor microenvironment. Curr Pharm Des 10(27):3431-42Nakamoto M and Bergmann AD (2002). Diverse roles for the Eph family of receptor tyrosine kinases incarcinogenesis. Microsc Res Tech 1; 59(1):58-67Ireton RC and Chen J (2005). EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.Curr Canc Drug Targets 5(3): 149-57
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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