Bfl-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Bfl-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bfl-1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by caspase activation. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such member is multi-domain antiapoptotic protein Bfl-1, which is overexpressed in stomach and other cancers. Bfl-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. It is upregulated in cisplatin-resistant human bladder tumors, suggesting that its expression may be important for cisplatin resistance and inhibition of apoptosis in cancer cells. At least two isoforms of Bfl-1 are known to exist. |
| Immunogen | Immunogen: Bfl-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Bfl-1. Buffer: Bfl-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Bfl-1; GRS; BFL1; ACC-1; ACC-2; HBPA1; BCL2L5; GRS; Bcl-2-related protein A1; Bcl-2-like protein 5; Bcl2-L-5; BCL2-related protein A1], [BCL2A1; BCL2A1; GRS; BFL1; ACC-1; ACC-2; HBPA1; BCL2L5; BCL2L5; BFL1; GRS; HBPA1; Bcl2-L-5] |
| Gene, Accession # | [BCL2A1], Gene ID: 597, NCBI: NP_004040, UniProt: Q16548 |
| Catalog # | MBS150416 |
| Price | $375 |
| Order / More Info | Bfl-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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