SIAH2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySIAH2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: SIAH2 antibody detects endogenous levels of total SIAH2. Function: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (GPS2, POU2AF1, PML, NCOR1), a cell surface receptor (DCC), an antiapoptotic protein (BAG1), and a pro
ImmunogenImmunogen: A synthesized peptide derived from human SIAH2 Subcellular Location: Cytoplasm. Nucleus. Predominantly Cytoplasmic (Probable). Partially Nuclear. Tissue Specificity: Widely expressed at low level.
Other Names[E3 ubiquitin protein ligase SIAH2; E3 ubiquitin-protein ligase SIAH1; hSIAH1; hSiah2; HUMSIAH; Seven in absentia homolog 1 (Drosophila); Seven in absentia homolog 1; Seven in Absentia Homolog 2; SIAH 1; Siah 1a; Siah 2; Siah-1; Siah-1a; Siah1; SIAH1_HUMAN; Ubiquitin ligase SIAH1; Ubiquitin Ligase Siah2]
Gene, Accession #[SIAH2], Gene ID: 6478, NCBI: NP_005058.3, UniProt: O43255
Catalog #MBS9608344
Price$240, $280
Order / More InfoSIAH2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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