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Antigenic Specificity | Dab1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dab1 Polyclonal Antibody detects endogenous levels of Dab1 protein. The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. DAB1 is similar to disabled-1, and the protein encoded by DAB1 is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of DAB1 have been reported, but their full length nature has not been determined. |
Immunogen | Immunogen: Synthesized peptide derived from human Dab1 around the non-phosphorylation site of Y232 |
Other Names | [Rabbit Dab1; DAB1; Disabled homolog 1] |
Gene, Accession # | [Dab1], Gene ID: 1600, NCBI: NP_066566.3, UniProt: O75553 |
Catalog # | MBS9701853 |
Price | $130, $220, $325 |
Order / More Info | Dab1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |