Edit |   |
---|---|
Antigenic Specificity | ACTN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ACTN1 antibody detects endogenous levels of total ACTN1. Description: Alpha-Actinin belongs to the spectrin family of cytoskeletal proteins. It was first recognized as an actin cross-linking protein, forming an antiparallel homodimer with an actin binding head at the amino terminus of each monomer. More recently, alpha-actinin has been shown to interact with a large number of proteins involved in signaling to the cytoskeleton including those involved in cellular adhesion, migration, and immune cell targeting (1). The interaction of alpha-actinin with intercellular adhesion molecule-5 (ICAM-5) helps to promote neurite outgrowth (2). In osteoblasts, interaction of alpha-actinin with integrins stabilizes focal adhesions and may pr |
Immunogen | Immunogen: A synthesized peptide derived from human ACTN1 Subcellular Location: Cytoplasm > Cytoskeleton. Cytoplasm > Myofibril > Sarcomere > Z Line. Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. |
Other Names | [actinin 1 smooth muscle; Actinin alpha 1; actinin, alpha 1; ACTN 1; Actn1; ACTN1_HUMAN; Alpha Actinin 1; Alpha actinin cytoskeletal isoform; Alpha-actinin cytoskeletal isoform; Alpha-actinin-1; BDPLT15; F actin cross linking protein; F-actin cross-linking protein; FLJ40884; FLJ54432; Non muscle alpha actinin 1; Non-muscle alpha-actinin-1] |
Gene, Accession # | [ACTN1], Gene ID: 87, NCBI: NP_001093.1, UniProt: P12814 |
Catalog # | MBS9606953 |
Price | $240, $280 |
Order / More Info | ACTN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |