Islet 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIslet 1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionRabbit IgG polyclonal antibody for Insulin gene enhancer protein ISL-1(ISL1) detection. Background: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence in the middle region of human Islet 1 (118-161aa DEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAE), identical to the related mouse and rat sequences.
Other Names[ISL 1; ISL1; Islet-1; Islet1; ISLET1; P61371; Insulin gene enhancer protein ISL-1; ISL LIM homeobox 1], [ISL1; ISL1; Isl-1; ISLET1; Islet-1]
Gene, Accession #[ISL1], Gene ID: 3670, NCBI: NP_002193.2, UniProt: P61371
Catalog #MBS178676
Price$315
Order / More InfoIslet 1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Entrez Gene: ISL1 ISL1 transcription factor, LIM/homeodomain, (islet-1).2. Gay F, Anglade I, Gong Z, Salbert G (October 2000). The LIM/homeodomain protein islet-1 modulates estrogen receptor functions. Mol. Endocrinol. 14 (10): 1627-48.3. Tanizawa Y, Riggs AC, Dagogo-Jack S, Vaxillaire M, Froguel P, Liu L, Donis-Keller H, Permutt MA (July 1994). Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected]. Diabetes. 43 (7): 935-41.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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