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Antigenic Specificity | TAB2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TAB2. It was validated on Western BlotTarget Description: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage c |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TAB2 |
Other Names | [TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform a; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAK1-binding protein 2; TAB-2; TGF-beta-activated kinase 1-binding protein 2] |
Gene, Accession # | [TAB2], Gene ID: 23118, NCBI: NP_055908, UniProt: Q9NYJ8 |
Catalog # | MBS3219613 |
Price | $335 |
Order / More Info | TAB2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |