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Antigenic Specificity | Phospho-Bik (T33) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.33 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Bik Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T33 of human Bik. The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. |
Immunogen | n/a |
Other Names | [Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4; BIK; NBK] |
Gene, Accession # | [BIK], Gene ID: 638, NCBI: NP_001188.1, UniProt: Q13323 |
Catalog # | MBS9212274 |
Price | $165, $370 |
Order / More Info | Phospho-Bik (T33) Antibody from MYBIOSOURCE INC. |
Product Specific References | Nikrad, M., et al., Mol. Cancer Ther. 4(3):443-449 (2005). Dong, F., et al., Infect. Immun. 73(3):1861-1864 (2005). Hur, J., et al., Proc. Natl. Acad. Sci. U.S.A. 101(8):2351-2356 (2004). Gillissen, B., et al., EMBO J. 22(14):3580-3590 (2003). Arena, V., et al., Genes Chromosomes Cancer 38(1):91-96 (2003). |