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Antigenic Specificity | PDIA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDIA3 is an isomerase enzyme, mapped on 15q15.3. The PDIA3 protein has protein disulfide isomerase activity. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex, which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface. Koivunen et al. showed that PDIA3 could not substitute for the beta subunit of PDI. When coexpressed with alpha prolyl 4-hydroxylase, PDIA3 did not form prolyl 4-hydroxylase tetramers, nor did it have prolyl 4-hydroxylase activity. Hirano et al. expressed human PDIA3 and found that the protein had a thiol-dependent reductase activity. They showed that the expression level of PDIA3 is increased after oncogenic |
Immunogen | Immunogen: PDIA3 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human PDIA3, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit PDIA3; PDIA3; PDIA3; PDIA 3; GRP58; PDIA 3; ER60; Erp57; PDIA-3; PDIA3; PDIA-3; Protein disulfide isomerase family A member 3] |
Gene, Accession # | [PDIA3], Gene ID: 2923, UniProt: P30101 |
Catalog # | MBS5312973 |
Price | $345 |
Order / More Info | PDIA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |